Essential Haematology is established as the most authoritative introduction to haematology. Beautifully presented, it introduces the formation and function of blood cells and diseases that arise from dysfunction and disruption of these processes. Basic science, diagnostic tests, clinical features and management are all clearly explained. The book outlines the basic principles of clinical and laboratory haematology and shows how manifestations of blood diseases can be explained by new knowledge of the disease processes.
For the first time, Essential Haematology is fully supported by a suite of online MCQs and answers, and is now available as a FREE enhanced Wiley Desktop Edition (upon purchase of the book).
- Thoroughly updated to reflect the latest research in this fast-moving field
- Contains summary boxes at the end of each chapter
- Includes an expanded treatment range and an expanded section on bone marrow failure and transplantation
ABOUT THE AUTHOR
Paul Moss is Professor of Haematology at the University of Birmingham, UK
TABLE OF CONTENTS
Preface to the First Edition ix
How to get the best out of your textbook x
1 Haemopoiesis 1
2 Erythropoiesis and general aspects of anaemia 15
3 Hypochromic anaemias 33
4 Iron overload 50
5 Megaloblastic anaemias and other macrocytic anaemias 58
6 Haemolytic anaemias 73
7 Genetic disorders of haemoglobin 88
8 The white cells 1: granulocytes, monocytes and their benign disorders 108
9 The white cells 2: lymphocytes and their benign disorders 126
10 The spleen 142
11 The aetiology and genetics of haematological malignancies 150
12 Management of haematological malignancy 166
13 Acute myeloid leukaemia 178
14 Chronic myeloid leukaemia 191
15 The non-leukaemic myeloproliferative neoplasms 200
16 Myelodysplasia 214
17 Acute lymphoblastic leukaemia 223
18 The chronic lymphoid leukaemias 234
19 Hodgkin lymphoma 245
20 Non-Hodgkin lymphoma 253
21 Multiple myeloma and related disorders 272
22 Aplastic anaemia and bone marrow failure 288
23 Stem cell transplantation 297
24 Platelets, blood coagulation and haemostasis 314
25 Bleeding disorders caused by vascular and platelet abnormalities 330
26 Coagulation disorders 345
27 Thrombosis and antithrombotic therapy 362
28 Haematological changes in systemic disease 381
29 Blood transfusion 397
30 Pregnancy and neonatal haematology 413
Appendices
1 Normal values 424
2 World Health Organization classifi cation of tumours of the haematopoietic and lymphoid tissues 426
Index 431
NEW TO THIS EDITION
- Further additions to the renowned clinical slide catalog including examples of PET-CT, molecular pathology and clinical signs
- Provides complete compliance with the WHO haematological malignancies classification of 2008
- Summary boxes at the end of each chapter to emphasize core learning elements
- Fully supported by a suite of online MCQs and answers
- Available as a FREE enhanced Wiley Desktop Edition (upon purchase of the textbook) - an interactive digital version of the book featuring downloadable text and images, highlighting and note taking facilities, book marking, cross-referencing, in-text searching, and linking to references and glossary terms
REVIEWS
"This is a great introductory book on clinical hematology. I'd recommend it for anyone early in their medical training or practice, or for any established practitioner wanting a quick refresher course in the subject." (Doody's, 2 September 2011)
"Much improved version. I liked the descriptive style where blocks of information gathered on same subject and easy for students to 'connect the dots'." (Athar Aziz, School of Environment & Life Sciences, University of Salford)
Reviews of the previous edition:
"This is a beautiful book ... packed with superb colour figures, laboratory and clinical illustrations, and is magnificently laid out. The text is clearly written, contains excellent, up-to-date background science, comprehensive clinical and laboratory data and sensible advice on the management of a full range of haematological disorders. My own students were delighted to see a copy and were unanimous in their view that this is a high quality bargain." (Journal of Clinical Pathology)
"The molecular and biochemical aspects of modern haematology are simply and clearly explained throughout, so encouraging students to read further from the comprehensive reading list at the end of each chapter.... It is a difficult book to fault and must take first place as the undergraduates' handbook for haematology." (British Medical Journal)
FEATURES
- The sixth edition of the best-selling introductory haematology textbook
- Written by leading haematology educators
- Provides complete compliance with the WHO haematological malignancies classification of 2008
- Thoroughly updated to reflect the latest research in this fast-moving fieldsuch as additions on tyrosine kinase inhibitors, lenalidomide, monoclonal antibodies and the oral anticoagulants,factor 10 and factor 2 inhibitors
- Further additions to the renowned clinical slide catalog including examples of PET-CT, molecular pathology and clinical signs
- Now contains summary boxes at the end of each chapter to aid understanding
- Supplemented by an online test-bank containing multiple choice questions and answers
- Available as an interactive enhanced Wiley Desktop Edition
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