Leukaemia is a cancer which starts in blood-forming tissue, usually the bone marrow. It leads to the over-production of abnormal white blood cells, the part of the immune system which defends the body against infection.Leukemia can happen when there is a problem with the production of blood cells. It usually affects the leukocytes, or white blood cells.
It is most likely to affect people over the age of 55 years, but it is also the most common cancer in those aged under 15 years.Leukaemia is the name given to a group of cancers that develop in the bone marrow. Under normal conditions the bone marrow contains a small number of healthy immature blood cells, sometimes called blast cells. These immature blood cells mature and develop into red cells, white cells and platelets, which are eventually released into the blood stream.
Leukaemia originates in developing blood cells, which have undergone a malignant (cancerous) change. Instead of maturing properly, these cells grow and multiply in an uncontrolled fashion and interfere with normal blood cell production in the bone marrow. Most cases of leukaemia originate in developing white cells. In a small number of cases leukaemia develops in other blood-forming cells, for example in developing red cells or developing platelets.
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